Table 2.

Selected examples of generalized reaction schemes from the PFAS environmental and metabolism reaction libraries including the measured half-lives. The parent PFAS on which the reaction scheme was based, associated reaction systems, and references are provided

Reaction scheme	Generalized reaction scheme	Parent PFAS	Reaction system	Half-life (reference)
Oxidation: fluorotelomer alcohol to fluorotelomer aldehyde intermediate			Aerobic soil/sediment	1.6 d (ref. 43)
				<7 d (ref. 25)
Oxidation: fluorotelomer alcohol to carboxylic acid with loss of methyl group			Aerobic soil/sediment	75 d (ref. 43)
				40 d (ref. 44)
Reduction: perfluoroalkyl sulfonyl fluoride to perfluoroalkyl sulfinic acid			Glutathione	1 d (ref. 45)
				0.4 d (ref. 45)
				1 d (ref. 45)
Reduction: sulfonamide to sulfinic acid			Digester sludge	40–100 d (ref. 46)
				40–100 d (ref. 46)