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. 2022 Aug 9;22:868. doi: 10.1186/s12885-022-09960-z

Table 2.

Clinicopathological characteristics and recurrence, according to biomarkers level in pre-nCRT sera

Variable APOA1 (n = 91) APOH (n = 91) S10A8 (n = 91) HEP2 (n = 91) GELS (n = 91) PZP (n = 91) PEDF(n = 91)
Low n = 46 High n = 45 P Low n = 46 High n = 45 P Low n = 46 High n = 45 P Low n = 46 High n = 45 P Low n = 46 High n = 45 P Low n = 46 High n = 45 P Low n = 46 High n = 45 P
Age, years
  Median 54 60 0.157 58 59.5 0.429 55 59.5 0.2286 59 58.5 0.5139 60 58 0.8310 55.46 59.26 0.0679 57.49 57.45 0.987
  Range 9.9 8.19 9.91 9.53 9.827 9.509 9.83 9.62 9.792 9.708 9.98 9.169 9.818 9.687
Gender
  Female 14 19 0.280 16 17 1.00 16 17 0.8292 15 18 0.5173 15 17 0.6641 10 23 0.0046 18 15 0.6641
  Male 32 26 28 30 30 28 31 27 31 28 36 22 28 30
Pathological T stage
  ypT0-2 13 29 0.0007 16 26 0.0361 17 25 0.0941 13 29 0.0007 12 30 0.0001 13 29 0.0007 15 27 0.0117
  ypT3-4 33 16 30 19 29 20 33 16 34 15 33 16 31 18
Pathological N stage
  ypN0 23 37 0.0018 30 32 0.654 29 33 0.3696 27 35 0.0717 25 37 0.0065 31 31 1.0 27 35 0.0717
  ypN1-2 23 8 16 13 17 12 19 10 21 8 15 14 19 10
Pathological complete response
  Yes 2 10 0.0141 6 6 1.0 4 8 0.2305 3 9 0.0695 2 10 0.0141 1 11 0.0017 4 8 0.2305
  No 44 35 40 39 42 37 43 36 44 35 45 34 42 37
Recurrence at any site
  Yes 9 7 1.0 8 8 1.0 4 12 0.0295 10 6 0.41 10 6 0.41 8 8 1.0 9 7 0.784
  No 37 38 38 37 42 33 36 39 36 39 38 37 37 38