Table 2.
Correlation between the expression of STAG3 and clinicopathological features in 126 HCC patients
| Clinicopathological features | Number (n = 126) | Low expression (n = 90) | High expression (n = 36) | χ2 | P value |
|---|---|---|---|---|---|
| Age, year | |||||
| ≤ 60 | 69 | 50 | 19 | 0.080 | 0.777 |
| > 60 | 57 | 40 | 17 | ||
| Gender | |||||
| Male | 103 | 76 | 27 | 1.537 | 0.215 |
| Female | 23 | 14 | 9 | ||
| AFP, ng/ml | |||||
| ≤ 20 | 52 | 31 | 21 | 6.054 | 0.014* |
| > 20 | 74 | 59 | 15 | ||
| Cirrhosis | |||||
| Negative | 71 | 45 | 26 | 5.163 | 0.023* |
| Positive | 55 | 45 | 10 | ||
| HBV | |||||
| Negative | 12 | 6 | 6 | 2.761 | 0.097 |
| Positive | 111 | 81 | 30 | ||
| HCV | 3 | 3 | 0 | ||
| Tumor size, cm | |||||
| ≤ 5 | 65 | 39 | 26 | 8.593 | 0.003** |
| > 5 | 61 | 51 | 10 | ||
| Pathological stage | |||||
| I-II | 41 | 24 | 17 | 4.950 | 0.026* |
| III-IV | 85 | 66 | 19 | ||
| Intrahepatic metastasis | |||||
| Negative | 114 | 81 | 33 | 0.083 | 0.773 |
| Positive | 12 | 9 | 3 | ||
STAG3, stromal antigen 3; HCC, hepatocellular carcinoma. *P < 0.05, **P < 0.01