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. 2022 Aug 9;251:196–201.e4. doi: 10.1016/j.jpeds.2022.07.056

Table III.

Demographic and clinical characteristics of patients hospitalized because of COVID-19 following vaccination

Age, y Sex Patient medical history Hospital course Hospital length of stay COVID-19 therapies
18 Female Premature ventricular contractions Symptoms: fever, cough, dyspnea, chest pain, vomiting, diarrhea
Supportive care: admitted for observation and intravenous fluids because of dehydration; no supplemental oxygen requirement
24 h No specific COVID-19 therapies
18 Female Heart transplantation for congenital heart disease complicated by heterotaxy and polysplenia
Patient has history of COVID-19 complicated by MIS-C in late 2020
Symptoms: fatigue, dyspnea, cough, sore throat
Supportive care: no supplemental oxygen requirement
4 d Remdesivir × 4 doses
Dexamethasone × 2 doses
20 Female Connective tissue disorder requiring methotrexate Symptoms: congestion, cough, diarrhea
Supportive care: admitted for observation and intravenous fluids because of dehydration; no supplemental oxygen requirement
48 h No specific COVID-19 therapies
17 Male Inherited endocrinopathy complicated by adrenal insufficiency Symptoms: fever, cough
Supportive care: in Emergency Department, developed hypotension and treated with stress-dose corticosteroids; no supplemental oxygen requirement
48 h No specific COVID-19 therapies

MIS-C, multisystem inflammatory syndrome in children. None of these patients experienced a coinfection caused by another respiratory virus.

Despite the lack of oxygen requirement, the patient was hospitalized for observation and received targeted COVID-19 treatment at the provider's discretion because of immunocompromising conditions and history of COVID-19 complicated by MIS-C.