Figure 5.

The anti-inflammatory activities of schaftoside on lipopolysaccharide (LPS)-induced acute lung injury (ALI) mice. (A) Experimental scheme⁴⁰. (B) Effects of schaftoside (10 and 20 mg/kg, i.g.) on histological changes of the mice (n = 4). Representative images of mice lung tissue stained with HE after 8 h of LPS treatment. (C) Pathology evaluation for the therapeutic effect of schaftoside; n = 4 and ∗∗∗P < 0.001⁴¹. (D) TNF-α, IL-6, and IL-1β levels of blood samples measured by mice ELISA kit. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 compared with the control group, n = 4. (E) Immunohistochemistry of lung tissues of LPS-induced ALI mice for TNF-α, IL-6, and IL-1β analysis.