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. 2022 Jan-Mar;23(1):18–25. doi: 10.18502/jri.v23i1.8447

Table 3.

The plasma level(s) of TNF-α, IL6, IL1ß, IL18, and CRP

Inflammatory factors Control PCOS TE+SPE50 TE+SPE200 TE+SPE600
TNF-α 293±3.21 373±2.10 # 355±2.21 * 348±3.07 *** 330±6.83 ***
IL-6 101±1.15 241±8.72 # 201±10.46 ** 183±5.57 *** 171±8.72 ***
IL-1ß 31.66±0.84 59.50±0.34 # 55.33±1.17 * 54.16±0.87 *** 54±0.99 ***
IL-18 316±10.54 410±8.56 # 363±9.18 ** 338±6 *** 336±4.21 ***
CRP 0.17±0.0004 0.32±0.0008 # 0.28±0.012 ** 0.26±0.007 *** 0.21±0.10 ***

Plasma TNF-α, IL6, IL1ß, IL18, and CRP level(s) were measured by using an ELISA kit. In PCOS groups treated with SPE, a significant reduction in levels of inflammatory factors (TNF-α, IL-6, IL-1ß, IL18, and CRP) was observed. All values are presented as the means±SEMs (n=12 per group).

TE, Testosterone enanthate; # p<0.001 vs. control, *** p<0.001, ** p<0.01, * p<0.05 vs. TE