Table 3.
The plasma level(s) of TNF-α, IL6, IL1ß, IL18, and CRP
Inflammatory factors | Control | PCOS | TE+SPE50 | TE+SPE200 | TE+SPE600 |
---|---|---|---|---|---|
TNF-α | 293±3.21 | 373±2.10 # | 355±2.21 * | 348±3.07 *** | 330±6.83 *** |
IL-6 | 101±1.15 | 241±8.72 # | 201±10.46 ** | 183±5.57 *** | 171±8.72 *** |
IL-1ß | 31.66±0.84 | 59.50±0.34 # | 55.33±1.17 * | 54.16±0.87 *** | 54±0.99 *** |
IL-18 | 316±10.54 | 410±8.56 # | 363±9.18 ** | 338±6 *** | 336±4.21 *** |
CRP | 0.17±0.0004 | 0.32±0.0008 # | 0.28±0.012 ** | 0.26±0.007 *** | 0.21±0.10 *** |
Plasma TNF-α, IL6, IL1ß, IL18, and CRP level(s) were measured by using an ELISA kit. In PCOS groups treated with SPE, a significant reduction in levels of inflammatory factors (TNF-α, IL-6, IL-1ß, IL18, and CRP) was observed. All values are presented as the means±SEMs (n=12 per group).
TE, Testosterone enanthate; # p<0.001 vs. control, *** p<0.001, ** p<0.01, * p<0.05 vs. TE