Table 2.
Frequency of alleles and genotypes of immune response genes in the group with iRM and control group
| Gene/polymorphism | Genotypes/alleles | Study group (N=302) n (%) | Control group (N=300) n (%) | p-value |
|---|---|---|---|---|
| CTLA4 (CT60 G/A) | ||||
| GG | 145 (48.0%) | 131 (43.7%) | 0.285 | |
| GA | 136 (45.0%) | 135 (45.0%) | 0.994 | |
| AA | 21 (7.0%) | 34 (11.3%) | 0.063 | |
| G | 426 (70.5%) | 397 (66.2%) | 0.121 | |
| A | 178 (29.5%) | 203 (33.8%) | 0.104 | |
| CX3CR1 (Val249Ile) | ||||
| Ile/Ile | 181 (60.0%) | 208 (69.3%) | 0.016 | |
| Val/Ile | 109 (36.1%) | 85 (28.3%) | 0.042 | |
| Val/Val | 12 (3.9%) | 7 (2.4%) | 0.250 | |
| Ile | 471 (78.0%) | 501 (83.5%) | 0.015 | |
| Val | 133 (22.0%) | 99 (16.5%) | 0.016 |