Appendix Table A1.

Area under the curve (AUC), specificity, sensitivity, and effect size between acute cases and uninjured adolescents for each of the 13 metrics significantly different between groups.

	Acute vs. Uninjured
	AUC (95% CI)	Specificity	Sensitivity	Effect Size (95% CI)
left.pupilsizemean	0.75 (0.69, 0.80)	0.77	0.67	0.84 (0.61, 1.08)
left.pupilsizemedian	0.75 (0.66, 0.86)	0.86	0.58	0.85 (0.61, 1.08)
right.pupilsizemean	0.75 (0.69, 0.81)	0.78	0.65	0.87 (0.63, 1.11)
right.pupilsizemedian	0.75 (0.70, 0.81)	0.81	0.63	0.87 (0.63, 1.10)
left.pupilsizemaxabs	0.70 (0.65, 0.76)	0.82	0.54	0.72 (0.48, 0.95)
right.pupilsizemaxabs	0.71 (0.65, 0.77)	0.9	0.44	0.75 (0.52, 0.98)
left.pupilsizeminabs	0.65 (0.59, 0.72)	0.4	0.9	0.58 (0.34, 0.81)
right.pupilsizeminabs	0.69 (0.59, 0.72)	0.45	0.9	0.74 (0.50, 0.97)
conj.pupilsizediffmean	0.66 (0.59, 0.72)	0.6	0.69	0.49 (0.26, 0.72)
conj.pupilsizediffmedian	0.65 (0.59, 0.71)	0.6	0.67	0.49 (0.26, 0.72)
conj.pupilsizediffvar	0.72 (0.66, 0.78)	0.75	0.65	0.37 (0.15, 0.60)
conj.varYbot	0.62 (0.55, 0.68)	0.66	0.58	0.10 (−0.12, 0.33)
conj.varYtopbotRatio	0.7 (0.55, 0.68)	0.44	0.8	0.25 (0.02, 0.48)