Appendix Table A3.

Area under the curve (AUC), specificity, sensitivity, and effect size between acute and persistent cases for each of the 13 metrics significantly different between groups.

	Acute vs. Persistent
	AUC (95% CI)	Specificity	Sensitivity	Effect Size (95% CI)
left.pupilsizemean	0.56 (0.48, 0.64)	0.68	0.51	0.22 (0.05, 0.49)
left.pupilsizemedian	0.56 (0.49, 0.64)	0.72	0.46	0.23 (0.05, 0.50)
right.pupilsizemean	0.58 (0.50, 0.66)	0.79	0.36	0.27 (0.00, 0.55)
right.pupilsizemedian	0.58 (0.50, 0.66)	0.75	0.42	0.27 (0.00, 0.55)
left.pupilsizemaxabs	0.54 (0.46, 0.61)	0.82	0.3	0.10 (−0.17, 0.38)
right.pupilsizemaxabs	0.55 (0.47, 0.63)	0.75	0.38	0.17 (−0.10, 0.44)
left.pupilsizeminabs	0.58 (0.50, 0.66)	0.85	0.3	0.27 (0.00, 0.54)
right.pupilsizeminabs	0.59 (0.52, 0.67)	0.54	0.69	0.30 (0.03, 0.57)
conj.pupilsizediffmean	0.51 (0.43, 0.59)	0.72	0.36	0.11 (−0.16, 0.38)
conj.pupilsizediffmedian	0.51 (0.43, 0.58)	0.62	0.46	0.10 (−0.20, 0.34)
conj.pupilsizediffvar	0.51 (0.43, 0.58)	0.85	0.26	0.25 (−0.02, 0.52)
conj.varYbot	0.61 (0.53, 0.68)	0.76	0.44	0.38 (0.11, 0.66)
conj.varYtopbotRatio	0.52 (0.44, 0.59)	0.4	0.73	0.08 (−0.20, 0.35)