Table 5.
Effect of C. citrinus over the biomarkers of oxidative stress in liver, heart, stomach, and kidney in rats fed with high fat-fructose diet (HFFD).
| Biomarkers oxidative stress in treatments | |||||
|---|---|---|---|---|---|
| Group | Organ | GSH (mM GSH/g tissue) |
MDA (nmol/mg protein) |
HNE (nmol/mg protein) |
PCO (µM PCO/mg protein) |
| Control | Liver | 2.90 ± 0.08 | 0.23 ± 0.02 | 0.14 ± 0.04 | 56.44 ± 3.61 |
| Heart | 2.33 ± 0.05 | 0.12 ± 0.01 | 0.03 ± 0.01 | 9.44 ± 2.67 | |
| Kidney | 48.32 ± 0.09 | 0.21 ± 0.00 | 0.09 ± 0.01 | 0.27 ± 0.01 | |
| Stomach | 26.55 ± 1.74 | 0.24 ± 0.09 | 0.15 ± 0.05 | 0.49 ± 0.04 | |
| HFFD | Liver | 1.90 ± 0.09* | 0.36 ± 0.03* | 0.48 ± 0.04* | 103.52 ± 4.17* |
| Heart | 1.03 ± 0.04* | 0.15 ± 0.01 | 0.17 ± 0.01* | 22.79 ± 2.67* | |
| Kidney | 54.00 ± 1.10* | 0.26 ± 0.01* | 0.22 ± 0.01* | 1.32 ± 0.21* | |
| Stomach | 19.69 ± 1.29* | 0.27 ± 0.08 | 0.34 ± 0.80* | 0.98 ± 0.05* | |
| HFFD + SIMV | Liver | 2.70 ± 0.08 | 0.31 ± 0.02 | 0.26 ± 0.04 | 55.88 ± 3.61 |
| Heart | 2.25 ± 0.04 | 0.11 ± 0.01 | 0.06 ± 0.01 | 9.42 ± 2.31 | |
| Kidney | 50.83 ± 0.24 | 0.24 ± 0.01 | 0.08 ± 0.01 | 0.37 ± 0.01 | |
| Stomach | 23.81 ± 1.87 | 0.25 ± 0.03 | 0.14 ± 0.09 | 0.59 ± 0.03 | |
| HFFD + C. citrinus | Liver | 3.00 ± 0.09 | 0.30 ± 0.02 | 0.31 ± 0.04 | 49.50 ± 4.17 |
| Heart | 2.27 ± 0.04 | 0.12 ± 0.01 | 0.06 ± 0.01 | 9.66 ± 2.67 | |
| Kidney | 47.94 ± 1.37 | 0.22 ± 0.00 | 0.06 ± 0.00 | 0.39 ± 0.01 | |
| Stomach | 23.29 ± 2.60 | 0.23 ± 0.07 | 0.17 ± 0.03 | 0.53 ± 0.05 | |
Values expressed as mean ± SEM (n = 6; Dunnett’s post hoc test, value of *p ≤ 0.05 vs. the control group is significant).