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. 2022 Aug 7;60(1):1384–1393. doi: 10.1080/13880209.2022.2099907

Table 5.

Effect of C. citrinus over the biomarkers of oxidative stress in liver, heart, stomach, and kidney in rats fed with high fat-fructose diet (HFFD).

Biomarkers oxidative stress in treatments
Group Organ GSH
(mM GSH/g tissue)
MDA
(nmol/mg protein)
HNE
(nmol/mg protein)
PCO
(µM PCO/mg protein)
Control Liver 2.90 ± 0.08 0.23 ± 0.02 0.14 ± 0.04 56.44 ± 3.61
Heart 2.33 ± 0.05 0.12 ± 0.01 0.03 ± 0.01 9.44 ± 2.67
Kidney 48.32 ± 0.09 0.21 ± 0.00 0.09 ± 0.01 0.27 ± 0.01
Stomach 26.55 ± 1.74 0.24 ± 0.09 0.15 ± 0.05 0.49 ± 0.04
HFFD Liver 1.90 ± 0.09* 0.36 ± 0.03* 0.48 ± 0.04* 103.52 ± 4.17*
Heart 1.03 ± 0.04* 0.15 ± 0.01 0.17 ± 0.01* 22.79 ± 2.67*
Kidney 54.00 ± 1.10* 0.26 ± 0.01* 0.22 ± 0.01* 1.32 ± 0.21*
Stomach 19.69 ± 1.29* 0.27 ± 0.08 0.34 ± 0.80* 0.98 ± 0.05*
HFFD + SIMV Liver 2.70 ± 0.08 0.31 ± 0.02 0.26 ± 0.04 55.88 ± 3.61
Heart 2.25 ± 0.04 0.11 ± 0.01 0.06 ± 0.01 9.42 ± 2.31
Kidney 50.83 ± 0.24 0.24 ± 0.01 0.08 ± 0.01 0.37 ± 0.01
Stomach 23.81 ± 1.87 0.25 ± 0.03 0.14 ± 0.09 0.59 ± 0.03
HFFD + C. citrinus Liver 3.00 ± 0.09 0.30 ± 0.02 0.31 ± 0.04 49.50 ± 4.17
Heart 2.27 ± 0.04 0.12 ± 0.01 0.06 ± 0.01 9.66 ± 2.67
Kidney 47.94 ± 1.37 0.22 ± 0.00 0.06 ± 0.00 0.39 ± 0.01
Stomach 23.29 ± 2.60 0.23 ± 0.07 0.17 ± 0.03 0.53 ± 0.05

Values expressed as mean ± SEM (n = 6; Dunnett’s post hoc test, value of *p ≤ 0.05 vs. the control group is significant).