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. 2022 Aug 7;60(1):1469–1477. doi: 10.1080/13880209.2022.2102656

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — PI3K/p-PI3K, AKT/p-AKT, Bcl-2/BAX and GSK-3β/β-actin expression in MCAO/R rats. (A) Expression of PI3K, p-PI3K, β-actin measured with western blot and protein expression of p-PI3K/PI3K. (B) Expression of Akt, p-Akt, β-actin measured with western blot and protein expression of p-Akt/Akt. (C) Expression of Bax, Bcl-2, β-actin measured with western blot and protein expression of Bcl-2/Bax. (D) Expression of GSK-3β, β-actin measured with western blot and protein expression of GSK-3β/β-actin. Results are expressed as mean ± SD and are compared with the sham group. * p < 0.05. ** p < 0.01 compared with the MCAO/R group. ^#p < 0.05. ^##p < 0.01 compared with the LY294002 group. ⁺p < 0.05. ⁺⁺p < 0.01.