Table 2.

Disease severity reported as median scores (and interquartile range) for EASI, BSA, itch-NRS, sleep-NRS, pain-NRS, POEM, and DLQI, at baseline, at week 4, and at week 16

	Baseline	Week 4	Week 16	p value*
Patients	n = 43	n = 26	n = 39
EASI score	26.0 (23.0–28.0)	3.5 (1.0–5.0)	0.0 (0.0–2.0)	< 0.001
BSA score	24.0 (20.0–30.0)	2.0 (0.0–4.0)	0.0 (0.0–2.0)	< 0.001
Itch-NRS score	9.0 (7.0–10.0)	2.0 (0.0–2.0)	0.0 (0.0–0.0)	< 0.001
Sleep-NRS score	8.0 (5.0–9.0)	1.0 (0.0–2.0)	0.0 (0.0–0.0)	< 0.001
Pain-NRS score	7.0 (0.0–8.0)	1.0 (0.0–1.0)	0.0 (0.0–0.0)	< 0.001
POEM score	18.0 (15.0–23.0)	3.5 (0.0–6.0)	0.0 (0.0–2.0)	< 0.001
DLQI score	16.0 (10.0–20.0)	2.5 (0.0–5.0)	0.0 (0.0–1.0)	< 0.001

*Wilcoxon rank test for dependent observations comparing baseline values with both week 4 and week 16 scores. The comparison was done list-wise

BSA Body Surface Area, DLQI dermatology life quality index, EASI eczema area severity index, NRS numeric rating scale, POEM patient-oriented eczema measure