Table 1.
Demographic characteristics, qSOFA score and steroid levels of COVID-19 patients
| Severe group (n = 43) | Moderate group (n = 60) | Mild group (n = 50) | Control group (n = 33) | *p | |
|---|---|---|---|---|---|
| AGE | 57 (22) | 15 (21) | 30 (14) | 27 (14) | <0.001a,b,d,e,f |
| Male (N;%) | 31 (34.1) | 39 (42.9) | 16 (17.6) | 5 (5.5) | <0.001a,b,c,d,e,f |
| Smoking (N;%) | 9 (21) | 6 (10) | 8 (16) | 0 | >0.05 |
| Patients without morbidity (N;%) | 28 (65.1) | 50 (83.3) | 47 (94) | – | <0.001d,e,f |
| qSOFA 0-1 (N;%) | 37 (86) | 59 (98) | 50 (100) | – | 0.016d,e,f |
| ALDOSTERONE pg/mL | 84.5 (16.4) | 89.9 (46) | 110.5 (75.3) | 7.74 (16.4) | <0.001a,b,c |
| 11 DEOXYCORTISOL** | 93.9 (224) | 497 (538) | 489 (512) | 13.5 (14.4) | <0.001a,b,c |
| 17- OH- PROGESTERONE** | 315 (542) | 625 (649) | 532 (417) | 26 (49.2) | <0.001a,b,c,e |
| CORTISOL ug/dL | 79.3 (154) | 149 (204) | 46.6 (73.7) | 10.4 (9.66) | <0.001a,b,c,e,f |
| CORTICOSTERONE** | 760 (1423) | 3382 (3769) | 2052 (1834) | 168 (243) | <0.001a,b,c,d,e |
| 11-DEOXYCORTICOSTERONE** | 66.5 (81) | 542 (697) | 747 (652) | 3.06 (3.81) | <0.001a,b,c,d,e |
| PREGNENOLENE** | 329 (561) | 510 (267) | 531 (462) | 111 (134) | <0.001a,b,c |
| 17-OH-PREGNENOLONE** | 14.4 (22.7) | 35.6 (43.8) | 41.6 (100) | 75.9 (132) | <0.001a,b,d,e |
| 21-DEOXYCORTISOL** | 35 (13) | 40 (17) | 42 (17) | 1.34 (1.73) | <0.001a,b,c,d |
Data are median (IQR); **, ng/dL
IQR interquartile rage
*Statistical significance was defined as p < 0.05
aSignificant difference between severe group and control group
bSignificant difference between moderate group and control group
cSignificant difference between mild group and control group
dSignificant difference between severe group and mild group
eSignificant difference between severe group and moderate group
fSignificant difference between moderate group and mild group