Table 1.
Demographic and infection characteristics of pregnant persons with SARS-CoV-2 infection by trimester of infection and disease severity.
| [Total unweighted number of persons with available information] Weighted %a (95% CI) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Trimester in which SARS-CoV-2 infection occurredb | COVID-19 severity | |||||||
| Characteristic | Total | 1st | 2nd | 3rdc | Mild | Moderate-to-severe | Critical | Asymptomatic |
| Total | [6336] | 13.9 (10.9–16.9) | 39.5 (35.5–43.5) | 46.6 (42.5–50.7) | 57.3 (53.1–61.5) | 25 (20.8–29.3) | 3.5 (2.5–4.5) | 14.2 (11.2–17.1) |
| Age (years) | [6333] | [991] | [2560] | [2782] | [3968] | [1267] | [283] | [815] |
| Median (IQR) | 29.4 (8.1) | 28.6 (7.2) | 29.9 (8.5) | 29.2 (8) | 29.2 (7.7) | 30.6 (8.1) | 32.3 (9) | 27.6 (8.3) |
| <20 | 4.7 (3.5–5.9) | 4.7 (2.4–7) | 4.1 (2.2–5.9) | 5.2 (3.2–7.2) | 4.1 (3–5.3) | 3.9 (1.1–6.6) | 8.4 (0–20.7) | 7.6 (3.1–12.1) |
| 20–24 | 17.7 (15.2–20.2) | 22.2 (12.9–31.6) | 17.1 (13.2–21) | 16.8 (13.7–19.9) | 18.6 (15.3–22) | 13.3 (9.2–17.3) | 6.7 (4.2–9.3) | 24.2 (16–32.5) |
| 25–29 | 31.3 (27.2–35.4) | 30.5 (21.1–40) | 29.1 (23–35.2) | 33.4 (26.9–39.9) | 35 (29.9–40.2) | 23.1 (16.9–29.4) | 23.8 (11.9–35.7) | 32.7 (18.8–46.5) |
| 30–34 | 27.8 (24.1–31.5) | 30.8 (17.4–44.3) | 28 (23.3–32.6) | 26.8 (21.3–32.3) | 26 (22.9–29.2) | 33.7 (22.4–45) | 35.5 (22.7–48.3) | 22.7 (15.7–29.7) |
| 35–39 | 14.9 (11.8–18) | 9.3 (6.5–12.2) | 17.9 (11.1–24.6) | 14.1 (11.2–17) | 12.4 (10.2–14.5) | 22.6 (12.2–32.9) | 21.4 (11–31.8) | 10.2 (6.4–14.1) |
| 40+ | 3.6 (2.4–4.7) | 2.3 (1.2–3.5) | 3.8 (1.3–6.4) | 3.7 (2.3–5) | 3.8 (1.9–5.7) | 3.5 (1.7–5.4) | 4.2 (2.4–6) | 2.6 (1.1–4.1) |
| Race/ethnicityd | [6150] | [973] | [2482] | [2695] | [3858] | [1229] | [269] | [794] |
| Asian, non-Hispanic | 4.4 (3.4–5.4) | 3.5 (2–5.1) | 3.7 (2.2–5.2) | 5.2 (3.4–7) | 3.9 (2.6–5.1) | 4.8 (2.3–7.2) | 7.4 (3.8–10.9) | 5.1 (1.4–8.7) |
| Black, non-Hispanic | 13.1 (10.9–15.2) | 25.7 (14.4–37.1) | 9.8 (8.2–11.3) | 12 (9.7–14.3) | 14.4 (11.1–17.8) | 9 (6.4–11.5) | 18.7 (11–26.3) | 13.4 (9.5–17.3) |
| Hispanic or Latino | 52.2 (48.4–56) | 44.9 (32.6–57.3) | 52.2 (46–58.4) | 54.4 (48.9–59.9) | 47.5 (42.8–52.2) | 55.7 (46–65.6) | 60 (48.1–71.9) | 62.6 (53.5–71.7) |
| White, non-Hispanic | 27.7 (24.7–30.6) | 23.6 (17.6–29.7) | 31.6 (26–37.2) | 25.5 (21.7–29.4) | 31 (27.4–34.6) | 28.5 (20.2–36.8) | 12.9 (8–17.9) | 16.5 (11.5–21.5) |
| Multiple or none of the above, non-Hispanic | 2.7 (2–3.4) | 2.1 (1.4–2.8) | 2.7 (1.6–3.9) | 2.9 (1.7–4) | 3.2 (2–4.3) | 2 (0.9–3.1) | 1 (0.3–1.8) | 2.5 (1.3–3.7) |
| Health insurance at delivery | [4745] | [680] | [1843] | [2222] | [2674] | [1107] | [180] | [784] |
| Private | 45.7 (40.9–50.5) | 44.1 (29–59.2) | 47.7 (40.1–55.4) | 44.4 (37.8–51) | 48.4 (42.7–54.1) | 43.5 (32–55) | 41.1 (23.9–58.3) | 41 (28.1–53.9) |
| Medicaid | 50.8 (46–55.5) | 53.5 (38.7–68.3) | 47.9 (40.6–55.1) | 52.4 (45.8–59) | 48.8 (43.2–54.5) | 51.7 (40.3–63) | 54.5 (37.4–71.7) | 55 (42.7–67.4) |
| Other/Self-pay/none | 3.6 (2.2–4.9) | 2.4 (1.4–3.5) | 4.4 (1.4–7.4) | 3.2 (1.9–4.5) | 2.8 (2–3.6) | 4.8 (0.3–9.4) | 3.9 (2–5.9) | 3.9 (2–5.9) |
| Maternal education | [4820] | [842] | [2018] | [1960] | [3256] | [922] | [191] | [451] |
| Less than high school | 12.2 (10.5–14) | 11.3 (7.4–15.2) | 11.1 (8.3–13.9) | 13.8 (11.1–16.6) | 12.6 (10.4–14.9) | 11.1 (7.7–14.4) | 22.3 (18.2–26.5) | 10.1 (5.1–15.1) |
| High school | 29.8 (25.2–34.4) | 26 (17.4–34.6) | 27.5 (22.2–32.8) | 33.8 (25–42.5) | 26.4 (22.9–30) | 29.8 (19.9–39.7) | 28.6 (23–34.2) | 48.7 (28.1–69.3) |
| Some college | 29.4 (24.7–34.1) | 38.4 (27.3–49.4) | 24.9 (19.8–30) | 30.3 (21.7–39) | 29.5 (24.9–34.2) | 32.7 (19–46.4) | 25.9 (19.6–32.2) | 22.8 (12.3–33.2) |
| College or greater | 28.6 (24–33.1) | 24.4 (19.2–29.6) | 36.5 (28–45) | 22.1 (17.9–26.2) | 31.4 (25.7–37.1) | 26.4 (16.6–36.3) | 23.2 (16.9–29.4) | 18.4 (10–26.8) |
| Underlying medical conditions | [5968] | [954] | [2405] | [2609] | [3778] | [1191] | [267] | [732] |
| Anye | 37.5 (33.8–41.2) | 29.2 (21.7–36.7) | 41.8 (35.4–48.3) | 36.5 (31.3–41.7) | 35.4 (31.4–39.6) | 43.2 (32.7–53.7) | 45.2 (32–58.4) | 33.7 (23.8–43.6) |
| Prepregnancy obesityf | 36.5 (33.2–39.8) | 26.9 (21.1–32.6) | 39.6 (33.7–45.5) | 37.2 (33.2–41.3) | 34.9 (31.1–38.8) | 41.6 (33–50.2) | 44.5 (33.5–55.5) | 32.9 (24.8–41) |
| Chronic lung disease | 13.7 (10.7–16.7) | 12 (6.7–17.3) | 13.3 (8–18.6) | 14.5 (10.1–18.9) | 11.3 (8.5–14) | 18 (9.9–26.1) | 12.4 (5.2–19.7) | 14.6 (5.3–23.9) |
| Chronic hypertension | 3.9 (3.2–4.7) | 3.8 (2.1–5.5) | 3.9 (2.9–4.8) | 4.1 (2.7–5.4) | 3.6 (2.8–4.4) | 3.5 (2–4.9) | 6.8 (3.6–10.1) | 5.3 (1.7–8.9) |
| Diabetes mellitus type 1 or 2 | 3.1 (1.7–4.5) | 1.3 (0.8–1.8) | 3.6 (0.7–6.5) | 3.2 (1.6–4.9) | 1.6 (1.1–2.1) | 6 (1.1–10.9) | 4.1 (1.6–6.6) | 3.8 (0–7.7) |
| Cardiovascular disease | 3.1 (2–4.2) | 1.9 (0.7–3.1) | 4.5 (1.7–7.2) | 2.3 (1.5–3.1) | 2.4 (1.7–3.1) | 3.8 (0.8–6.7) | 16.5 (0–35.1) | 1.3 (0.5–2) |
| Immunosuppression | 1.4 (1–1.8) | 1.9 (0.4–3.3) | 2 (1–3.1) | 0.8 (0.6–1.1) | 1.8 (1.1–2.6) | 0.5 (0.2–0.9) | 4.2 (1–7.4) | 0.8 (0–1.6) |
| Pregnancy-related condition | [5929] | [950] | [2408] | [2571] | [3760] | [1187] | [266] | [716] |
| Gestational diabetes | 12.3 (9.2–15.4) | 12.2 (5.3–19.2) | 14.7 (8–21.4) | 10.3 (8–12.5) | 11.3 (8.5–14.1) | 15.8 (5.6–26) | 18.6 (10.4–26.8) | 8.9 (4.5–13.2) |
| Hypertensive disorders in pregnancyg | 13.1 (10.8–15.4) | 16.6 (8.5–24.7) | 13.6 (9.7–17.5) | 11.6 (8.9–14.2) | 12.8 (9.9–15.7) | 12.4 (7.8–16.9) | 11.6 (6.7–16.6) | 15.7 (7.9–23.6) |
| Delivery status | [6336] | [992] | [2561] | [2783] | [3969] | [1268] | [283] | [816] |
| Term | 89 (87.4–90.6) | 92.6 (90.1–95) | 90.7 (88.2–93.1) | 86.6 (83.9–89.3) | 92.4 (91.1–93.7) | 90 (86.4–93.5) | 62.5 (49.7–75.4) | 80.3 (73.3–87.2) |
| Preterm | 11 (9.4–12.6) | 7.4 (5–9.9) | 9.3 (6.9–11.8) | 13.4 (10.7–16.1) | 7.6 (6.3–8.9) | 10 (6.5–13.6) | 37.5 (24.6–50.3) | 19.7 (12.8–26.7) |
| Extremely preterm (22–27 weeks) | 5.5 (1.2–9.7) | 7.2 (3.3–11) | 14.2 (2.5–25.9) | – | 2.3 (1.3–3.4) | 2.7 (0.8–4.6) | 22.3 (0–50.1) | 4.9 (0.1–9.6) |
| Early preterm (28–31 weeks) | 9.6 (5.1–14.1) | 5.7 (2.1–9.4) | 17.2 (5.6–29) | 5.8 (3.4–8.1) | 7.2 (3.6–10.7) | 7.3 (1.5–13.2) | 13.2 (6.7–19.7) | 13.7 (0–28.8) |
| Moderately preterm (32–33 weeks) | 9.7 (5.9–13.5) | 10.1 (5.1–15.2) | 7.4 (4–10.7) | 11 (4.7–17.3) | 9.6 (5.2–13.9) | 12.7 (0–26.4) | 14.8 (6.4–23.2) | 4.8 (2.5–7) |
| Late preterm (34–36 weeks) | 75.3 (68.8–81.7) | 77 (69.3–84.7) | 61.2 (48–74.4) | 83.3 (76.7–89.9) | 80.9 (75.5–86.4) | 77.2 (63.1–91.3) | 29.7 (29.2–70.2) | 76.7 (61.5–91.8) |
| Trimester in which SARS-CoV-2 infection occurred | [6336] | – | – | – | [3969] | [1268] | [283] | [816] |
| First | 13.9 (10.9–16.9) | – | – | – | 16.9 (13.6–20.1) | 12.9 (3.7–22.1) | 3.6 (2.4–4.8) | 6.4 (4.4–8.4) |
| Second | 39.5 (35.5–43.5) | – | – | – | 39.4 (34.8–43.9) | 44 (33.5–54.4) | 44.4 (30.2–58.5) | 30.9 (21.8–40) |
| Thirdc | 46.6 (42.5–50.7) | – | – | – | 43.7 (39.1–48.3) | 43.1 (32.9–53.3) | 52.1 (38.3–65.9) | 62.7 (52.9–72.5) |
| Severity of COVID-19 | [6336] | [992] | [2561] | [2783] | ||||
| Mild | 57.3 (53.1–61.5) | 69.4 (55.9–82.9) | 57.2 (50.6–63.7) | 53.9 (47.8–59.9) | – | – | – | – |
| Moderate-to-severe | 25 (20.8–29.3) | 23.2 (8.8–37.6) | 27.8 (21–34.7) | 23.1 (17.6–28.7) | – | – | – | – |
| Critical | 3.5 (2.6–4.5) | 0.9 (0.6–1.2) | 3.9 (2–5.9) | 3.9 (2.7–5.2) | – | – | – | – |
| Asymptomatic | 14.2 (11.2–17.1) | 6.5 (4.4–8.6) | 11 (7.9–14.3) | 19 (13.5–24.6) | ||||
SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, COVID-19 coronavirus disease 2019.
aPercentages may not sum to 100 due to rounding.
bBased on date of first positive test.
cExcludes persons infected at ≥37 weeks.
dPregnant persons with reported race and ethnicity information were grouped as Hispanic or non-Hispanic White, Asian, Black, multiple, or other. Multiple or other race/ethnicity contains American Indian or Alaska Native, Native Hawaiian or other Pacific Islander, other race as reported by jurisdictions, and more than one race indicated. Pregnant persons with missing or unknown ethnicity and non-Hispanic ethnicity with missing race were considered missing race/ethnicity.
eIncludes one or more of the following underlying medical conditions: prepregnancy obesity, chronic lung disease, chronic hypertension, diabetes mellitus type 1 or 2, cardiovascular disease, and immunosuppression.
fPrepregnancy obesity defined as body mass index ≥30 kg/m2.
gIncludes pregnancy-induced hypertension (gestational hypertension), preeclampsia, eclampsia, and hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome.