Skip to main content
. 2022 Jul 26;12:826450. doi: 10.3389/fcimb.2022.826450

Table 4.

Mono versus combination therapy of antibiotics against biofilm infections (bactericidal rate; 128× MIC; IMP: 160 mg/kg and GM: 64 mg/kg; in vivo).

Time Non-Treatment Imipenem (IMP)* Gentamicin (GM) IMP + GM#
Day 1 0.00 8.78% 84.8%& 92.52%
Day 3 0.00 2.95% 22.3% 47.54%
Day 7 0.00 2.68% 19.1% 38.48%

*IMP mono compared to non-treatment, no significance. &GM compared with IMP and non-treatment at day 1 after infection, p < 0.0001. #Combination compared to non- or monotherapy of IMP or GM, p < 0.03.