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. 2022 Aug 9;17(8):e0271824. doi: 10.1371/journal.pone.0271824

Table 3. Relative impact of predictors on Generalized Anxiety Disorder (GAD-7) score in responses over the year of surveys.

Association between GAD-7 and predictor at each survey time period 1,2 Change in association between GAD-7 and predictor over the year 1,2
Survey 1 (Initial; N = 684) Survey 2 (3-month; N = 553) Survey 3 (12-month; N = 439)
Predictors O.R. 95%CI P-value O.R. 95%CI P-value O.R. 95%CI P-value O.R. 95%CI P-value
Change in GAD-7 over 1 year 3 1.13 (0.89, 1.44) 0.31
Individual predictors
Current home/family stress 2.13 (1.82, 2.50) <0.001 1.97 (1.72, 2.25) <0.001 1.40 (1.09, 1.80) 0.008 0.66 (0.49, 0.89) 0.007
Poor clinical team support 1.27 (1.11, 1.45) 0.001 1.36 (1.21, 1.53) <0.001 1.82 (1.47, 2.26) <0.001 1.43 (1.11, 1.84) 0.005
Future home/family stress 1.18 (1.01, 1.39) 0.041 1.14 (0.99, 1.30) 0.063 0.97 (0.74, 1.27) 0.81 0.82 (0.59, 1.13) 0.23
Inadequacy of information 1.16 (1.01, 1.33) 0.039 1.14 (1.01, 1.29) 0.028 1.09 (0.87, 1.37) 0.46 0.94 (0.72, 1.23) 0.66
Future financial stress 1.16 (0.98, 1.38) 0.079 1.15 (0.99, 1.32) 0.062 1.08 (0.77, 1.51) 0.67 0.93 (0.62, 1.38) 0.70
Poor ability for quality care 1.13 (0.98, 1.30) 0.082 1.14 (1.02, 1.29) 0.025 1.21 (0.96, 1.53) 0.11 1.07 (0.82, 1.41) 0.62
Covid ward status 1.10 (0.97, 1.25) 0.13 1.07 (0.96, 1.19) 0.22 0.94 (0.75, 1.18) 0.58 0.85 (0.65, 1.11) 0.23
Excessive information 1.10 (0.97, 1.24) 0.13 1.09 (0.98, 1.21) 0.11 1.05 (0.86, 1.27) 0.65 0.95 (0.76, 1.20) 0.68
Concerned about PPE 1.10 (0.96, 1.26) 0.16 1.10 (0.98, 1.24) 0.097 1.10 (0.89, 1.37) 0.37 1.00 (0.78, 1.30) 0.98
Smoking 1.07 (0.95, 1.20) 0.28 1.08 (0.97, 1.19) 0.15 1.12 (0.96, 1.31) 0.15 1.05 (0.86, 1.27) 0.63
Poor access to rapid tests 1.04 (0.92, 1.18) 0.54 1.05 (0.94, 1.17) 0.39 1.08 (0.88, 1.33) 0.46 1.04 (0.81, 1.33) 0.76
Enough deployment training 1.04 (0.91, 1.18) 0.60 1.03 (0.92, 1.16) 0.57 1.02 (0.83, 1.26) 0.84 0.99 (0.77, 1.26) 0.91
Public sector 1.03 (0.91, 1.17) 0.63 1.03 (0.92, 1.15) 0.61 1.02 (0.80, 1.30) 0.89 0.99 (0.74, 1.31) 0.92
Social situation 1.03 (0.90, 1.17) 0.68 1.02 (0.91, 1.13) 0.76 0.97 (0.80, 1.19) 0.79 0.95 (0.75, 1.21) 0.66
Lower staff grade 0.99 (0.87, 1.12) 0.88 0.99 (0.89, 1.11) 0.88 1.00 (0.80, 1.24) 0.97 1.01 (0.78, 1.31) 0.96
Current financial stress 0.99 (0.83, 1.18) 0.89 1.04 (0.89, 1.20) 0.63 1.27 (0.92, 1.76) 0.15 1.29 (0.88, 1.89) 0.19
Higher education level 0.94 (0.83, 1.06) 0.31 0.92 (0.83, 1.03) 0.16 0.87 (0.70, 1.07) 0.18 0.93 (0.73, 1.18) 0.54
Intensity of exposure 0.91 (0.79, 1.05) 0.19 0.95 (0.84, 1.07) 0.37 1.12 (0.91, 1.38) 0.30 1.22 (0.95, 1.58) 0.12
Males 0.85 (0.76, 0.96) 0.007 0.85 (0.77, 0.94) 0.002 0.84 (0.68, 1.02) 0.083 0.98 (0.78, 1.24) 0.88
Age group 0.75 (0.66, 0.85) <0.001 0.72 (0.64, 0.80) <0.001 0.61 (0.49, 0.76) <0.001 0.82 (0.64, 1.05) 0.11

1 Associations between predictors and outcomes, and change in outcomes over 1 year were estimated using repeated-measures ordered logistic regression; the effects were shown as odds ratios (O.R.; 95% confidence intervals; P-values), adjusted for each of the predictors shown in the tables; missing data was substituted by multiple imputation. Odds ratios of 1.00 indicate no association; O.R. more than 1.00 indicate a positive association; O.R. less than 1.00 indicate a negative association.

2 The association between predictors and outcomes in the surveys were estimated for the mean survey completion dates for each survey, set as the zero value of the time interaction predictor: (date of each survey completion by specific respondent minus the mean date of each survey completion). Mean date of survey completion was: Survey 1, 0.1 years on 6/05/2020; Survey 2, 0.29 years on 13/07/2020; Survey 3, 1.1 years 8/05/2021. The change in association between each predictor and outcomes was determined by the time interaction.

3 Model fit parameters: Log likelihood (null) -4675.94; Log likelihood (model) -4320.87; df 62; Akaike information criterion (AIC) 8765.744; Bayesian information criterion (BIC) 9102.042