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. 2022 Aug 9;13:4677. doi: 10.1038/s41467-022-32149-8

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2022

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Fig. 6 — Morbidity of mice vaccinated with a single dose of mRNA-LNPs containing monovalent or pentavalent formulations following I.N. challenge with 5mLD₅₀ of B/Lee/1940 (n = 5) (a) B/Malaysia/2506/2004 (V) (n = 5) (b), B/New York City/PV01181/2018 (V) (n = 5 for all groups except M2 where one mouse was found dead on day 1) (c), B/Florida/04/2006 (Y) (n = 5) (d), or B/New York City/PV00094/2017 (Y) (n = 4) (e) influenza viruses 4 weeks after immunization. Data are shown as the group mean and error bars represent SD. Survival of mice vaccinated with a single dose of mRNA-LNPs containing monovalent or pentavalent formulations following I.N. challenge with 5mLD₅₀ of B/Lee/1940 (f), B/Malaysia/2506/2004 (V) (g), B/New York City/PV01181/2018 (V) (h), B/Florida/04/2006 (Y) (i), or B/New York City/PV00094/2017 (Y) (j) influenza viruses 4 weeks after immunization. Source data are provided as a source data file.