Fig. 4.

Impact of RXB pretreatments (75 and 150 mg/kg) for Con A-challenged mice on the immunohistochemical expression and quantification of cleaved caspase 3 (A, C, 400×,), F4/80 (B, D, 100×,) and the activity of MPO (E) in the liver (n = 6–8/group). Arrows indicate apoptotic hepatocytes and arrowheads indicate infiltrated inflammatory cells. *, ** and *** denote a P-value (vs. the Control) less than 0.05, 0.01 and 0.001, respectively, but # and ## denote a P-value (vs. the Con A) less than 0.05 and 0.01, respectively.