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. 2022 Aug 9;4(9):e667–e675. doi: 10.1016/S2589-7500(22)00125-X

Table 1.

Characteristics of v-safe respondents with reports related to menstruation or vaginal bleeding compared with total female v-safe respondents

Respondents reporting menstrual irregularities or vaginal bleeding (n=63 815) Total female v-safe respondents aged ≥18 years*(n=5 975 363)
Sex
Female 62 679 (98·2%) 5 975 363 (100·0%)
Male 368 (0·6%) ..
Other 206 (0·3%) ..
Unknown 562 (0·9%) ..
Age group
18–49 years 57 997 (90·9%) 3 095 361 (51·8%)
50–64 years 5307 (8·3%) 1 698 520 (28·4%)
65–74 years 422 (0·7%) 887 481 (14·9%)
75–84 years 82 (0·1%) 249 567 (4·2%)
85+ years 7 (<0·1%) 44 434 (0·7%)
Race
White 49 795 (78·0%) 4 078 154 (68·2%)
Black 4866 (7·6%) 442 955 (7·4%)
Asian 4929 (7·7%) 412 249 (6·9%)
American Indian or Alaska Native 1230 (1·9%) 67 631 (1·1%)
Native Hawaiian or other Pacific Islander 440 (0·7%) 32 988 (0·6%)
Other 2948 (4·6%) 218 213 (3·7%)
Missing 2685 (4·2%) 849 895 (14·2%)
Ethnicity
Hispanic or Latino 8116 (12·7%) 619 917 (10·3%)
Not Hispanic or Latino 52 850 (82·8%) 4 421 916 (74·0%)
Missing 2851 (4·5%) 933 538 (15·6%)
Vaccine received
BNT162b2 33 149 (51·9%) 2 975 438 (49·8%)
mRNA-1273 26 741 (41·9%) 2 794 014 (46·8%)
Ad26.COV2.S 4072 (6·4%) 285 775 (4·8%)
Other/unknown 3 (<0·1%) 1662 (<0·1%)
Reported dose§
1 54 180 (84·9%) 4 935 274 (82·6%)
2 55 428 (86·9%) 4 221 380 (70·6%)
≥3 11 366 (17·8%) 745 158 (12·5%)
Submitted survey§
Dose 1
0–7 days 51 828 (81·2%) 4 725 436 (79·1%)
14 days 46 934 (73·5%) 3 766 825 (63·0%)
21 days 28 079 (44·0%) 2 292 256 (38·4%)
28 days 8222 (12·9%) 607 862 (10·2%)
35 days 4594 (7·2%) 216 797 (3·6%)
42 days 4435 (6·9%) 174 458 (2·9%)
3 months 3994 (6·3%) 358 875 (6·0%)
6 months 3575 (5·6%) 468 299 (7·8%)
12 months 321 (0·5%) 57 155 (1·0%)
Dose 2
0–7 days 52 752 (82·7%) 3 920 283 (65·6%)
14 days 46 192 (72·4%) 3 262 994 (54·6%)
21 days 44 570 (69·8%) 3 113 097 (52·1%)
28 days 42 958 (67·3%) 2 982 212 (49·9%)
35 days 42 625 (66·8%) 2 913 033 (48·8%)
42 days 41 545 (65·1%) 2 864 136 (47·9%)
3 months 41 537 (65·1%) 2 827 283 (47·3%)
6 months 38 616 (60·5%) 2 783 393 (46·6%)
12 months 469 (0·7%) 50 053 (0·8%)

Data are n (%).

*

Includes respondents who did and did not report menstrual irregularities or vaginal bleeding.

Includes 192 individuals with responses that were unrelated or not definitively related to menstruation (eg, “I suffer from cluster headache and I am in the middle of a cycle”), ten individuals reporting symptoms experienced by someone else, and four individuals who specifically mention being transgender in the response.

150 respondents with responses related to menstruation or vaginal bleeding and 81 465 female v-safe respondents received vaccine doses from more than one manufacturer.

§

Includes v-safe entries that do not mention menstruation, vaginal bleeding, or other free-text symptoms.