Table 5.

Effects on Tf, TfR, DMT1, TRPC6, and FPN1 in rats with CIRI induced by MCAO.

Group	Tf	TfR	DMT1	TRPC6	FPN1
Sham	34.032 ± 2.21	62.834 ± 4.59	78.772 ± 9.21	47.284 ± 6.32	95.252 ± 3.03
Model	81.342 ± 7.09∗∗	98.41 ± 1.10∗∗	103.354 ± 0.97∗∗	94.036 ± 2.62∗∗	63.832 ± 6.10∗∗
RAP granule	50.776 ± 3.08##	49.764 ± 10.15##	86.286 ± 5.36#	56.57 ± 10.53##	81.296 ± 3.35#
RAP injection	62.93 ± 6.69#	63.328 ± 2.69##	71.254 ± 6.45##	67.334 ± 10.31#	80.212 ± 5.90
Calycosin	70.198 ± 8.62	66.638 ± 6.94##	88.046 ± 6.28	62.706 ± 8.00#	74.014 ± 5.21
Edaravone	55.828 ± 6.41##	66.584 ± 4.64##	96.762 ± 1.14	69.536 ± 13.00	83.408 ± 7.97#
Deferoxamine	74.832 ± 4.65	74.164 ± 9.22#	89.366 ± 3.83	66.376 ± 7.69#	80.142 ± 6.42

Results of the IHC data are expressed as the mean ± SEM, n = 5. ^∗∗P < 0.01 vs. sham group. ^#P < 0.05 and ^##P < 0.01 vs. model group.