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Optimized fluid management. The optimal fluid management is based on defining the indication (trigger), predicting fluid responsiveness and evaluating the response to fluids both in terms of increase in perfusion but also taking into account tolerance to fluids. CRT capillary refill time, CO cardiac output, CVP central venous pressure, EVLW lung edema (estimated by various ways including transpulmonary thermodilution or lung ultrasounds, VS venous stasis
