Table 3.

Univariable Cox regression analyses for the volumes of interest of TLG

	Overall survival			Disease-free survival
	HR (95% CI)ª	p-value	C-index	HR (95% CI)ª	p-value	C-index
T TLG with SUV2.5 threshold	1.001 (10,004–1.003)	0.009	0.652	1.003 (1.001–1.004)	0.001	0.693
N TLG with SUV2.5 threshold	1.002 (1.001–1.003)	0.005	0.586	1.001 (1.001–1.002)	0.014	0.586
T + N with TLG SUV2.5 threshold	1.001 (1.001–1.002)	0.001	0.660	1.001 (1.001–1.002)	< 0.001	0.706
T TLG with background-level threshold	1.001 (1.01–1.001)	0.281	0.629	1.001 (1.01–1.001)	0.245	0.671
N TLG with background-level threshold	1.002 (1.001–1.003)	0.006	0.545	1.001 (1.001–1.002)	0.020	0.566
T + N TLG with background-level threshold	1.001 (1.001–1.002)	0.001	0.649	1.001 (1.001–1.002)	< 0.001	0.694

ªPer unit increment

HR hazard ratio, CI confidence interval, TLG total lesion glycolysis, C-index Harrell’s C-index, SUV standardized uptake value, T tumor, N lymph node