Table 3.
iAUC values for postprandial glucose, insulin, IL-1β, IL-6 and endothelial adhesion molecules
| Parameter | High inflammation group | Low inflammation group |
P value inflammation × meal |
P value inflammation effect | P value meal effect | ||||
|---|---|---|---|---|---|---|---|---|---|
| MED | WDHF | WDHC | MED | WDHF | WDHC | ||||
| Glucose iAUC (h*mmol/L) | 4.8 ± 1.2 | 3.6 ± 0.6 | 6.5 ± 1.3 | 3.8 ± 0.8 | 2.9 ± 0.5 | 3.9 ± 0.61 | 0.735 | 0.096 | 0.016 |
| Insulin iAUC (h*pmol/L) | 1556 ± 159 | 1447 ± 127 | 2095 ± 229 | 1884 ± 266 | 1405 ± 139 | 2238 ± 275 | 0.344 | 0.577 | < 0.001 |
| IL-1β iAUC (h*pg/mL) | 0.04 ± 0.03 | 0.03 ± 0.04 | 0.03 ± 0.04 | − 0.03 ± 0.02 | 0.01 ± 0.02 | 0.01 ± 0.01 | 0.480 | 0.197 | 0.759 |
| IL-6 iAUC (h*pg/mL) | 14.9 ± 3.1 | 9.1 ± 3.1 | 11.4 ± 2.8 | 13.5 ± 3.0 | 7.4 ± 2.2 | 9.6 ± 2.9 | 0.912 | 0.645 | 0.269 |
| sE-Selectin iAUC (h*ng/mL) | − 1.2 ± 1.6 | − 7.2 ± 1.5 | − 5.9 ± 2.1 | − 4.1 ± 1.5 | − 3.9 ± 1.7 | − 5.7 ± 2.4 | 0.238 | 0.174 | 0.884 |
| sICAM-1 iAUC (h*ng/mL) | − 11.7 ± 10.9 | − 21.3 ± 16.6 | 2.4 ± 15.5 | 5.0 ± 12.0 | − 14.0 ± 15.8 | − 29.6 ± 21.1 | 0.261 | 0.818 | 0.450 |
| sVCAM-1 iAUC (h*ng/mL) | − 86.7 ± 38.4 | − 104.4 ± 47.4 | − 133.2 ± 43.5 | − 75.1 ± 34.1 | − 31.2 ± 43.2 | − 52.5 ± 39.8 | 0.668 | 0.098 | 0.827 |
Values given as mean ± SEM
MED Mediterranean diet-like meal, IL-1β interleukin-1β, IL-6 interleukin-6, sE-selectin soluble E-selectin, sICAM-1 soluble intercellular adhesionmolecule-1, sVCAM-1 soluble vascular cell adhesionmolecule-1, WDHC Western diet-like high-carbohydrate meal, WDHF Western diet-like high-fat meal