Table 4.
Simple regression of clinical outcomes with healthy controls.
| Clinical symptoms and scales | Intercept | AAA |
|---|---|---|
| H&Y | 0.00 | 0.00 |
| MDS-UPDRS III | −3.70 | 0.12″ |
| MDS-UPDRS II | −0.21 | 0.02′ |
| LEDD (g/day) | −0.02 | 0.00′ |
| Gait disorder* | −12.56 | 0.13″ |
| Repetitive falls* | −5.14 | 0.00 |
| MDS-UPDRS IV | 0.00 | 0.00 |
| Dyskinesia/day (hours) | 0.00 | 0.00 |
| OFF time/day (hours) | 0.00 | 0.00 |
| Dystonia/day (hours) | 0.00 | 0.00 |
| Dyskinesia* | −26.57 | 0.00 |
| Motor fluctuations* | −26.57 | 0.00 |
| Freezing of gait* | −26.57 | 0.00 |
| MoCA | 29.84 | −0.05″ |
| Sniffin’ stick test | 15.44 | −0.04″ |
| PDQ-39 | 10.68 | −0.01 |
| SCOPA-AUT | 2.53 | 0.08″ |
| MDS-UPDRS I | 3.12 | 0.02 |
| BDI-I | 4.06 | 0.02 |
| Starkstein Apathy Scale | 5.11 | 0.07″ |
| PDSS | 130.37 | −0.13 |
| Probable RBD* | −1.58 | −0.02 |
| Excessive daily sleepiness* | −6.53 | 0.05 |
| Insomnia* | −2.00 | −0.01 |
| Hallucinations* | −3.31 | −0.04 |
| Impulse Control Disorder* | −4.32 | −0.04 |
| Orthostatic hypotension* | −3.92 | 0.02 |
| Dysphagia* | −7.28 | 0.04 |
| Constipation* | −2.37 | −0.01 |
| Urinary Incontinence* | −8.43 | 0.08″ |
Regression coefficients are shown from linear regression of numerical outcome and from logistic regression of binary outcome on age at assessment (AAA). Single and double ticks indicate significance at the 5% level and the Bonferroni adjusted 5% level, the bold indicates significant effect where minus value indicates negative significant effect and positive value positive significant effect respectively. The binary variables are annotated by asterisk. Clinical symptoms and scales are described in Supplementary Material.