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. 2022 Aug 9;13:4680. doi: 10.1038/s41467-022-32472-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Schematic representation of the DPF3 splicing isoforms and the corresponding protein structures. b Expression analysis of DPF3 in normal kidney tissues (n = 72 individuals) and ccRCC patients from the TCGA-KIRC cohort (n = 534 individuals). Results represent median expression levels with 25 and 75% quartile. Y-axis represents the expression values of expectation-maximization (RSEM). Statistical significance was estimated using a two-sided Wilcoxon test. c Expression analysis of each exon of DPF3 (exon 6 to exon 12) in normal kidney tissues (n = 72 individuals) and ccRCC patients of the TCGA-KIRC cohort (n = 534 individuals). Results represent median expression levels with 25 and 75% quartile. Each dot represents one individual. Y-axis represents the expression values of expectation-maximization (RSEM).