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. 2022 Aug 9;5:798. doi: 10.1038/s42003-022-03768-0

Table 1.

Aggregation kinetics.

Protein tlag (h)a k b t1/2 (h)c
FL-α-syn 7.4 ± 0.4 0.65 ± 0.03 10.5 ± 0.3
CT-α-syn 2.1 ± 0.3 1.1 ± 0.1 4.0 ± 0.3
Y39E-α-syn NDd NDd NDd
FL-α-syn +PDI 23 ± 2 0.28 ± 0.05 30 ± 3
CT-α-syn +PDI 4.0 ± 0.3 0.7 ± 0.1 6.9 ± 0.6
Y39E-α-syn+PDI 36 ± 2 0.21 ± 0.03 46 ± 1

aLag time.

bElongation rate constant.

cHalf-time of aggregation.

dPlateau was not reached.