. Author manuscript; available in PMC: 2023 Dec 1.

Published in final edited form as: Alzheimers Dement. 2022 Feb 10;18(12):2518–2526. doi: 10.1002/alz.12573

TABLE 2.

Associations^* of selected volumetric magnetic resonance imaging (MRI) findings with APOE ε4 carrier status

	N	β (95% CI)	P	P (age)
Brain volume	758	0.02 (−0.05, 0.09)	.594	<.001
Hippocampus volume	756	−0.05 (−0.21, 0.11)	.548	.003
Left hippocampus volume	757	−0.01 (−0.20, 0.18)	.916	.001
Right hippocampus volume	757	−0.08 (−0.21, 0.05)	.217	.005

Generalized linear regression model, Gaussian (normal) link, bootstrap variance-covariance estimator (VCE) with 50 replications; adjusted for intracranial volume, age, sex, field center, education, BMI, diabetes, hypertension, high LDL, and CKD. Standardized volumetric exposure and adjustment variables, for direct comparisons.