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. 2022 Jul 27;13:888644. doi: 10.3389/fimmu.2022.888644

Figure 5.

Figure 5

Causal relationships of interleukins on OSA risk by Mendelian randomization (MR) analysis. (A) The design of MR analysis was to explore the causal effects of interleukin levels on OSA risk: interleukins as exposure, OSA as outcomes, and SNPs independently associated with interleukins were used as instrumental variables. Other two assumptions are the same as described in the legend of Figure 4A. (B) The presented results were performed by method of inverse-variance weighting (IVW). IL, interleukin.