Table 1.
Characteristics of the included studies about interleukin levels in patients with OSA and control.
| Study ID | Region | PMID | Researched protein | P/CNo. | NOS |
|---|---|---|---|---|---|
| Kotsiou O.S., 2022 | Greece | 34678476 | IL-6 | 15/15 | 6 |
| Bhatt S.P., 2021 | India | 34086720 | IL-6, IL-8, IL-10, IL-17, IL-23 | 190/57 | 7 |
| Bilal N., 2021 | Turkey | 32776303 | IL-6, IL-8 | 30/30 | 8 |
| Cheng J., 2021 | China | 34488706 | IL-8 | 29/22 | 6 |
| Chen B., 2021 | China | 33942365 | IL-1β | 67/30 | 8 |
| Celikhisar H., 2020 | Turkey | 32454912 | IL-1β | 84/82 | 8 |
| Chen V.G., 2020 | Brazil | 30213594 | IL-1β, IL-4, IL-6, IL-8, IL-10 | 17/17 | 5 |
| Dalesio N.M., 2020 | US | 31688081 | IL-1β, IL-6, IL-10 | 7/18 | 5 |
| Huang Y.S., 2020 | China | 32260590 | IL-1β, IL-6, IL-10, IL-12, IL-17, IL-23 |
55/32 | 9 |
| Ming H., 2019 | China | 30783447 | IL-8 | 684/192 | 8 |
| Tang T., 2019 | China | 30284175 | IL-1β, IL-6, IL-18 | 120/127 | 7 |
| Shi C., 2019 | China | 29453637 | IL-2 | 15/15 | 8 |
| Zhang D., 2019 | China | 30542936 | IL-8 | 21/10 | 7 |
| Bozic J., 2018 | Croatia | 29991422 | IL-6 | 50/25 | 8 |
| Kong Y., 2018 | China | 29843666 | IL-1β, IL-6 | 50/40 | 5 |
| Lu D., 2018 | China | 28707162 | IL-6 | 35/22 | 6 |
| Mônico-Neto M., 2018 | Brazil | 30093572 | IL-6 | 447/211 | 5 |
| Rogers V.E., 2018 | US | 29862666 | IL-10, IL-12 | 20/7 | 5 |
| Shalitin S., 2018 | Israel | 29305826 | IL-6 | 9/29 | 6 |
| Gamsiz-Isik H., 2017 | Turkey | 27858556 | IL-1β | 83/80 | 8 |
| Jin F., 2017 | China | 28901415 | IL-8 | 100/50 | 8 |
| Said E.A., 2017 | Oman | 28830779 | IL-2, IL-4, IL-8, IL-10, IL-12 |
22/21 | 6 |
| Smith D.F., 2017 | US | 28204724 | IL-6, IL-8 | 65/90 | 5 |
| Su M., 2017 | China | 28500380 | IL-4, IL-10 | 42/48 | 7 |
| Toujani S., 2017 | Tunisia | 28469721 | IL-17 | 92/30 | 8 |
| Zhang Z., 2017 | China | 28367199 | IL-2, IL-4, IL-6, IL-10 | 50/52 | 5 |
| Archontogeorgis K., 2016 |
Greece | 27843647 | IL-8 | 64/20 | 7 |
| Can M., 2016 | Turkey | 27665460 | IL-23 | 12/27 | 6 |
| Dogan D., 2016 | Turkey | 27346160 | IL-6 | 39/12 | 8 |
| Huang Y.S., 2016 | China | 27741107 | IL-1β, IL-6, IL-10, IL-17, IL-23 |
47/32 | 6 |
| Ifergane G., 2016 | Israel | 27073238 | IL-6 | 21/22 | 8 |
| Nizam N., 2016 | Turkey | 26232894 | IL-6 | 39/13 | 7 |
| Zychowski K.E., 2016 | US | 27693879 | IL-6 | 8/7 | 6 |
| Damiani M.F., 2015 | Italy | 26697221 | IL-6 | 30/30 | 7 |
| Leon-Cabrera S., 2015 | Mexico | 25944984 | IL-10, IL-12 | 29/13 | 6 |
| Nobili Y., 2015 | Italy | 26069285 | IL-6 | 52/28 | 8 |
| Sarinc Ulasli S., 2015 | Turkey | 25724552 | IL-2, IL-10 | 28/20 | 6 |
| Ye J., 2015 | China | 25860501 | IL-4, IL-17 | 25/19 | 8 |
| Zhang S.W., 2015 | China | - | IL-18 | 66/25 | 8 |
| Ciccone M.M., 2014 | Italy | 24481114 | IL-6 | 80/40 | 7 |
| Gileles-Hillel Alex, 2014 | US | 24991089 | IL-6 | 75/129 | 9 |
| Akinnusi M., 2013 | US | 23239459 | IL-4, IL-6, IL-8, IL-10 |
25/18 | 8 |
| Kurt O.K., 2013 | Turkey | 23783568 | IL-6 | 48/37 | 7 |
| Yang D., 2013 | China | 23567762 | IL-6 | 25/25 | 7 |
| Deboer M.D., 2012 | US | 21360253 | IL-6 | 9/15 | 7 |
| Medeiros C. A. M., 2012 | Brazil | 21916851 | IL-1β, IL-6 | 50/15 | 7 |
| Qian X., 2012 | China | 22527145 | IL-6 | 30/40 | 6 |
| Ye J., 2012 | China | 23345934 | IL-6, IL-10, IL-17 | 44/20 | 9 |
| Liu Z., 2011 | China | - | IL-6 | 20/20 | 8 |
| Kim J., 2010 | Korea | 20855682 | IL-6, IL-8 | 37/22 | 6 |
| Sahlman J., 2010 | Finland | 20040038 | IL-1β, IL-6, IL-10 | 84/40 | 7 |
| Steiropoulos P., 2010 | Greece | 20628509 | IL-6 | 38/23 | 8 |
| Ye L., 2010 | China | 20668869 | IL-6 | 127/52 | 7 |
| Li Y., 2009 | China | 18207457 | IL-6, IL-10 | 68/22 | 7 |
| Li C., 2009 | China | 19187612 | IL-18 | 52/18 | 8 |
| Antonopoulou S., 2008 | Greece | 18606530 | IL-6 | 45/25 | 7 |
| Arias M.A., 2008 | Spain | 18508832 | IL-6 | 30/15 | 9 |
| Constantinidis J., 2008 | Greece | 18317790 | IL-1β, IL-6 | 13/12 | 7 |
| Li Y., 2008 | China | 18311073 | IL-6, IL-10 | 28/22 | 5 |
| Nakra N., 2008 | US | 18762497 | IL-6 | 24/9 | 7 |
| Takahashi K.I., 2008 | Japan | 18199002 | IL-6 | 41/12 | 7 |
| Tomiyama H., 2008 | Japan | 18224268 | IL-6, IL-1β | 50/15 | 8 |
| Chen J., 2007 | China | - | IL-6 | 100/40 | 6 |
| Tauman R., 2007 | US | 17171553 | IL-6 | 78/33 | 8 |
| Bao H.R., 2005 | China | - | IL-8, IL-10 | 35/25 | 7 |
| Ciftci T.U., 2004 | Turkey | 15381186 | IL-6 | 43/22 | 6 |
| Liu H., 2000 | China | 11215046 | IL-6 | 22/16 | 6 |
| Roytblat L., 2000 | Israel | 11225716 | IL-6 | 11/9 | 5 |
IL, interleukin; P/C No., number of patients with OSA (P) and controls (C) in each group; NOS represents Newcastle-Ottawa Scale, which is used for article quality evaluation.
For the references for each study, please refer to Supplemental Table 2.