Figure 3.

(Color online) Effect of lanthanum hydroxide treatment on vascular calcification in rats with chronic kidney disease (CKD) and hyperphosphatemia. (A) Drug treatment after 4 weeks. (B) Drug treatment after 8 weeks. (a) Serum calcium. (b) Serum phosphorus. (c) Serum PTH. (d) Serum FGF23 ( $\overline{\text{X}}\pm \text{S}$ , compared with the control group, ^##p < 0.01; compared with the model group, *p < 0.05, **p < 0.01, n = 15, ns: not significant). (C) Hematoxylin and eosin (HE) staining of thoracic aortic tissues of CKD rats. (D) Von Kossa staining of thoracic aortic tissues of CKD rats. (E) EVG staining of thoracic aortic tissues of CKD rats (n = 5).