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Inhibitory activity of NOEV (27) and its N-alkyl homologues against three glycosidases
| Compd | Inhibitory activity (IC50, µM) | ||
|---|---|---|---|
|
| |||
| α-Galactosidase (green coffee beans) | β-Galactosidase (bovine liver) | β-Glucosidase (almonds) | |
| 27: n = 7 | 3.1 | 0.87 | 3.1 |
| 154a: n = 5 | 2.7 | 2.3 | 1.2 |
| b: n = 9 | 1.9 | 0.13 | 2.5 |
| c: n = 11 | 4.4 | 0.01 | 0.87 |
