Table 3.
List of Enriched KEGG Pathways in RGCs Co-Cultured With Astrocytes and RGCs Treated With CNTF
| RGCs + Astrocytes | RGCs + CNTF Treatment | |||
|---|---|---|---|---|
| KEGG Pathway | P Value | FDR | P Value | FDR |
| Olfactory transduction | 0.008482852 | 0.028099448 | 3.94478E-08 | 9.74362E-06 |
| Hepatitis C | 0.001805703 | 0.011041232 | 5.89496E-07 | 4.85352E-05 |
| Metabolic pathways | 2.72084E-12 | 7.21023E-10 | 2.95463E-06 | 0.000182449 |
| Human papillomavirus infection | 9.46109E-08 | 4.17865E-06 | 4.96167E-05 | 0.00152346 |
| PI3K/Akt signaling pathway | 0.00054035 | 0.004646518 | 0.00015513 | 0.003326039 |
| JAK/STAT signaling pathway | 0.003727101 | 0.016812323 | 0.000161589 | 0.003326039 |
| MAPK/ERK signaling pathway | 2.34192E-06 | 6.20608E-05 | 0.000655807 | 0.012460331 |
| Pathways in cancer | 7.73424E-10 | 6.83191E-08 | 0.000800177 | 0.014117417 |
| Influenza A | 0.001568909 | 0.010660536 | 0.001599311 | 0.023237052 |
| Measles | 0.011288239 | 0.034383717 | 0.00346524 | 0.039814879 |
RGCs, retinal ganglion cells; CNTF, ciliary neurotrophic factor; KEGG, Kyoto Encyclopedia of Genes and Genomes; FDR, false discovery rate.