Table 4.
Genes Identified as Upregulated or Downregulated Through RNA Sequencing and Associated Biological Processes
| Official Gene Symbol | log2 (Fold Change) | P Value | Full Description of the Gene | Gene Ontology Biological Process |
|---|---|---|---|---|
| Upregulated | ||||
| Acss3 | 1.0535 | 0.042 | acyl-CoA synthetase short-chain family member 3 | |
| Bcl3 | 2.2983 | 0.020 | BCL3, transcription coactivator | Intrinsic apoptotic signaling pathway in response to DNA damage, negative regulation of receptor signaling pathway via JAK-STAT, negative regulation of receptor signaling pathway via STAT, response to light stimulus |
| Clu | 1.4798 | <0.001 | Clusterin | Intrinsic apoptotic signaling pathway in response to DNA damage |
| Grm6 | 1.2321 | 0.001 | Glutamate metabotropic receptor 6 | Detection of light stimulus, detection of light stimulus involved in sensory perception, detection of light stimulus involved in visual perception, detection of visible light, response to light stimulus, sensory perception of light stimulus, visual perception |
| Junb | 1.3722 | 0.008 | JunB proto-oncogene, AP-1 transcription factor subunit | |
| Scube1 | 1.4343 | 0.009 | Signal peptide, CUB domain and EGF like domain containing 1 | |
| Shisa5 | 1.4861 | 0.009 | shisa family member 5 | Intrinsic apoptotic signaling pathway in response to DNA damage |
| Socs3 | 2.7084 | 0.003 | Suppressor of cytokine signaling 3 | Negative regulation of receptor signaling pathway via JAK-STAT, negative regulation of receptor signaling pathway via STAT |
| Downregulated | ||||
| Aipl1 | −1.059 | 0.002 | Aryl hydrocarbon receptor-interacting protein-like 1 | Detection of light stimulus, detection of visible light, response to light stimulus, sensory perception of light stimulus, visual perception |
| Dgkd | −1.067 | 0.003 | Diacylglycerol kinase, delta | |
| Fam57b | −1.29 | 0.012 | TLC domain containing 3B | |
| Igsf9 | −1.059 | 0.026 | Immunoglobulin superfamily, member 9 | |
| Nrl | −1.649 | 0.038 | Neural retina leucine zipper | Camera-type eye photoreceptor cell differentiation |
| Pdc | −1.477 | 0.018 | Phosducin | |
| Rom1 | −1.225 | 0.005 | Retinal outer segment membrane protein 1 | Camera-type eye photoreceptor cell differentiation, detection of light stimulus, detection of light stimulus involved in sensory perception, detection of light stimulus involved in visual perception, detection of visible light, response to light stimulus, sensory perception of light stimulus, visual perception |
| Sema6c | −1.23 | 0.048 | Semaphorin 6C | |
| Slc6a6 | −1.048 | 0.036 | Solute carrier family 6 member 6 |
Genes that showed infinite fold change or did not show consistent results between three experimental samples were excluded.