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. 2022 Jul 27;13:888221. doi: 10.3389/fneur.2022.888221

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Copyright © 2022 Xu, Huang, Xie and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sex-dependent analysis of serum miR-4297 and FHGRS. (A) Rather than FHGRS, statistically significant correlates are observed between miR-4297 levels and MPVs in female patients; (B) MGMT protein correlates with miR-4297 levels and FHGRS in females; (C) IDH-MT female patients have significantly decreased levels of miR-4297 and FHGRS. MPV, mean platelet volume; MGMT, O6-methylguanine-DNA methyltransferase; WT, wild type; MT, mutant type.