Table 2.
KEGG topological analysis.
| Pathways | VIP value | P- value | |
|---|---|---|---|
| Ex/HFD | |||
| 1 | Alanine, aspartate and glutamate metabolism | 0.27 | 0.01 |
| 2 | D-glutamine and D-glutamate metabolism | 0.22 | 0.04 |
| FA/HFD | |||
| 1 | D-glutamine and D-glutamate metabolism | 0.62 | <0.01 |
| 2 | Alanine, aspartate and glutamate metabolism | 0.57 | <0.01 |
| 3 | Glutathione metabolism | 0.29 | <0.01 |
| 4 | Aminoacyl-tRNA biosynthesis | 0.16 | <0.01 |
| 5 | Arginine and proline metabolism | 0.10 | <0.01 |
| Ex-FA/HFD | |||
| 1 | Glutathione metabolism | 0.29 | 0.01 |
| 2 | Alanine, aspartate and glutamate metabolism | 0.19 | 0.01 |
VIP value > 0.1 and P-value < 0.05 were listed. HFD, high-fat diet group (model); Ex, high-fat diet with exercise; FA, high-fat diet with ferulic acid; Ex-FA, high-fat diet with exercise and ferulic acid.