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. 2022 Jun 11;298(8):102132. doi: 10.1016/j.jbc.2022.102132

Table 1.

Affinity of tau for nucleic acid sequences

Inducer KDAPP kon (M−1 s−1) koff (s−1)
polyA 20 nM 1.0 X 104 1.4 X 10−4
polyU 254 nM 1.7 X 103 4.2 X 10−4
polyC 13 nM 3.7 X 104 4.5 X 10−4
ssDNA seq1 12 nM 2.8 X 104 3.4 X 10−4

Abbreviations: KDAPP, apparent binding affinity; kon, association rate; koff, dissociation rate.

Results were calculated as the mean of three independent experiments.