Effect of smart hydrogel on diabetic wounds. A) Gross view of diabetic wound treated with gauze, MMP-PEG hydrogel or ADSC-exo@MMP-PEG smart hydrogel; B) Measurement shown in A, ∗p < 0.05 vs. control, ∗∗p < 0.01 vs. control, ∗∗∗∗p < 0.001 vs. control, #p < 0.05 vs. MMP-PEG hydrogel group, ####p < 0.001 vs. MMP-PEG hydrogel group; C&D) H&E and Masson staining of wound sections at 14 days post wounding.