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. 2022 Aug 9;5(8):e2225582. doi: 10.1001/jamanetworkopen.2022.25582

Table 3. Interaction Between Prior Substance Use Disorder Treatment and Study Group on the Risk of Enrollment in Substance Use Disorder Program Within 30 Days of Enrollment in the Triala.

Study group No prior treatment exposure Prior treatment exposure Prior treatment exposure (yes vs no) within strata of study groups, RR (95% CI) P value
No. enrolled in SUD program (yes/no) RR (95% CI) P value No. enrolled in SUD program (yes/no) RR (95% CI) P value
Social worker 53/185 1 [Reference] NA 45/42 2.31 (1.69-3.16) <.001 2.31 (1.69-3.16) <.001
Peer 52/182 1.00 (0.71-1.40) >.99 51/38 2.51 (1.86-3.39) <.001 2.51 (1.86-3.40) <.001
Study groups (peer vs social worker) within strata of prior treatment exposure, RR (95% CI) NA 1.00 (0.71-1.40) >.99 NA 1.09 (0.83-1.42) .55 NA NA

Abbreviations: NA, not applicable; RR, relative risk; SUD, substance use disorder.

a

Log binomial regression models adjusted for the following randomization blocking variables: age category (<50 years), sex at birth, and hospital site.