Table 1. Trial Characteristics.
Sourcea | Dates of enrollment | No. of patients | Total No. of graftsb | No. of SVGs | Experimental group | Control group | Treatment duration, mo | Type of graft imaging | Time to graft imaging, mo | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Treatment | No. of patients with SVGs | No. of SVGs | Treatment | No. ofpatients with SVGs | No. of SVGs | ||||||||
TAP-CABG,8 2016 | 2011-2014 | 70 | 167 | 76 | Ticagrelor 90 mg 2/d + aspirin 81 mg 1/d | 19 | 34 | Placebo + aspirin 81 mg 1/d | 23 | 42 | 3 | CT angiography | 3 |
DACAB,9 2018 | 2014-2015 | 500 | 1146 | 712 | Group 1: ticagrelor 90 mg 2/d + aspirin 100 mg 1/d | 167 | 239 | Aspirin 100 mg 1/d | 166 | 242 | 12 | CT or coronary angiography | 12 |
Group 2: ticagrelor 90 mg 2/d | 166 | 231 | |||||||||||
TARGET,11 2022 | 2014-2019 | 250 | 688 | 373 | Ticagrelor 90 mg 2/d | 127 | 187 | Aspirin 81 mg 2/d | 123 | 186 | 12 | CT angiography | 12 |
POPular CABG,10 2020 | 2015-2019 | 496 | 1078 | 507 | Ticagrelor 90 mg 2/d + aspirin 80 mg or 100 mg 1/d | 249 | 254 | Placebo + aspirin 80 mg or 100 mg 1/d | 247 | 253 | 12 | CT angiography | 12 |
Abbreviations: CT, computed tomography; SVG, saphenous vein graft.
See the Methods section for the full names of the studies.
Includes SVGs and arterial grafts (left and/or right internal thoracic artery, and radial artery).