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. Author manuscript; available in PMC: 2022 Aug 10.
Published in final edited form as: Immunohorizons. 2022 Feb 10;6(2):116–129. doi: 10.4049/immunohorizons.2000072

Figure 3.

Figure 3.

Antimicrobial response including Pigr expression are lower in Il17ra−/− and Il17a/f−/− mice. A) At 3 months post infection, Pigr was measured in gastric tissue of H. pylori–infected WT, Il17a−/−, Il17f−/−, Il17a/f−/− and Il17ra−/− mice (n=5 per genotype). Relative units are calculated as described in the methods, relative to Gapdh expression and calibrated to uninfected WT mice. These data were not performed on additional mice (See Table III for reproducibility) B) At 3 months post infection, Defb14 was measured in H. pylori–infected WT and these other genotypes (n=5 per genotype). Relative units are calculated as described in the methods, relative to Gapdh and calibrated to uninfected WT mice. Statistical significance among groups was determined with Dunnett’s multiple comparison. Error bars represent ± SEM; *P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001 compared to WT.