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Cell viability assay after 24 h for (A) RAW 264.7 and (B) 16-HBE cells treated with free Roflumilast (black), LPHFNPs (pink), LPHFNPs@Roflumilast (red), Man-LPHFNPs (light blue), and Man-LPHFNPs@Roflumilast (blue). (*P < 0.05; **P < 0.001).
