Table 4.

T-cell and antibody responses in household contacts of COVID-19 patients evaluated at both time points (T0 and T1).

		T0			T1
		Positive swab N = 8	Negative swab N = 20	Tot N =28	Positive swab N = 9	Negative swab N = 19	Tot N = 28	P value*
Positive T-cell responders N over total		4 (50)	2 (10)	6 (21.4)	7 (77.8)	5 (26.3)	12 (42.8)	0.335
	Pool S responders [N (% among positive T-cell responders)]	4 (100)	2 (100)	6 (100)	7 (100)	3 (60)	10 (83.3)	0.335
	Pool N responders [N (% among positive T-cell responders)]	3 (75)	1 (50)	4 (66.7)	6(85.7)	1 (20)	7 (58.3)	0.345
	Pool M responders [N (% among positive T-cell responders)]	1 (25)	2 (100)	3(50)	4 (57.1)	4 (80)	8 (66.7)	0.294
Positive antibody responders N over total		1 (12.5)	1(5)	2 (7.1)	4 (44.4)	1 (10.5)	5 (41.7)	0.606
	anti-RBD responders [N (% among positive T-cell responders)]	1 (100)	1 (100)	2 (100)	3 (75)	1 (100)	4 (80)	0.576
	anti-N responders [N (% among positive T-cell responders)]	1 (100)	1 (100)	2 (100)	4 (100)	1 (100)	5 (100)	0.606

S, spike; N, nucleocapsid; M, membrane; RBD, receptor binding domain. *Chi-square test calculated among swab positive responders at the two time points.