TABLE 1.

⁶⁴Cu-DOTA-Trastuzumab Uptake and TTF

Tumor uptake		Patients > threshold		Patients ≤ threshold
Metric	Cut point (g/mL)*	n	Median TTF (mo)	n	Median TTF (mo)	Hazard ratio	P †
Day 1 average SUVmax	4.6	5	18	5	3	0.3 (0.1−1.3)	0.10
Day 2 average SUVmax	5.5	6	23	3	2	0.1 (0.0−0.9)	0.01
Day 1 minimum SUVmax	4.6	4	26	6	3	0.3 (0.1−1.3)	0.09
Day 2 minimum SUVmax	5.5	5	28	4	2	0.1 (0.0−1.0)	0.02

^*Optimal threshold relating uptake to response for individual tumors.

^†Log rank test.

Hazard ratios are >cut point relative to ≤cut point. Data in parentheses are 95% CIs.