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. 2022 Aug;63(8):1169–1176. doi: 10.2967/jnumed.121.262866

TABLE 2.

Cox Proportional Hazards Model for RFS and OS in Relation to Clinicopathologic Parameters and 68Ga-uPAR and 18F-FDG Uptake

RFS OS
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
Parameter Variable n HR 95% CI P HR 95% CI P HR 95% CI P HR 95% CI P
Sex Women 9
Men 45 3.666 0.486–27.657 0.208 3.109 0.410–23.578 0.273
Age*
0.993 0.943–1.046 0.802 1.035 0.984–1.090 0.184
Smoking <30 pack years 29
>30 pack years 25 1.129 0.433–2.947 0.804 3.072 1.060–8.906 0.039
TNM stage S1–2 32
S3–4 22 3.458 1.211–9.875 0.020 2.702 0.827–8.832 0.100 6.724 2.117–21.355 0.001 4.309 1.239–14.984 0.022
p16 Positive 26
Negative 28 2.361 0.864–6.456 0.094 1.006 0.331–3.064 0.991 4.615 1.314–16.212 0.017 1.712 0.438–6.691 0.440
68Ga-uPAR <Cutoff 13
>Cutoff 41 8.530 1.124–64.743 0.038 8.511 1.082–66.949 0.042 7.439 0.981–56.415 0.052 4.584 0.583–36.044 0.148
18F-FDG <Cutoff 42
>Cutoff 12 3.266 1.231–8.662 0.017 2.240 0.724–6.933 0.162 7.098 2.602–19.360 0.000 4.285 1.362–13.479 0.013
*

Age was included as continuous covariate.