FIGURE 4.

Kinetics of metastases and comparative results from 96 metastases (bone, lymph node, liver, lung, and other) of patients treated with ¹⁷⁷Lu-PSMA I&T and from 179 tumor lesions (bone, lymph node, liver, lung, and other) of patients treated with ¹⁷⁷Lu-PSMA-617. (A) Median kinetics of all types of metastases. (B) Median kinetics of bone metastases. (C) Median kinetics of lymph node metastases. After administration of therapeutic activity, higher initial uptakes and faster washout for ¹⁷⁷Lu-PSMA I&T were observed in bone and lymph node lesions. In contrast, curves of ¹⁷⁷Lu-PSMA-617 showed initial increase until 3 h after injection. %IA = percentage injected activity.