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. Author manuscript; available in PMC: 2022 Aug 10.
Published in final edited form as: Adv Biol Regul. 2018 Oct 27;71:118–127. doi: 10.1016/j.jbior.2018.10.006

Fig. 1. The kinase activities of IPMK, IP3K, and IP6K in the pathway of inositol phosphate synthesis in mammals.

Fig. 1.

Each individual inositol phosphate is abbreviated as follows: ‘Ins’ refers to inositol; the subscripts denote the total number of phosphates (‘P’), and the numbers in parentheses describe the positions of the phosphate groups around the inositol ring. Note that ‘5-InsP7’ denotes an ‘inositol pyrophosphate’ that has a diphosphate group at the 5-position. Arrows depict metabolic steps, catalyzed by the following enzymes, with E.C. numbers in parentheses: 1, IPMK, inositol polyphosphate multikinase (2.7.1.151; also known as IPK2); IP3K, inositol trisphosphate 3-kinase (2.7.1.127); INPP5, inositol polyphosphate 5-phosphatase, (3.1.3.56); ITPK1, inositol trisphosphate 6-kinase/ inositol tetrakisphosphate 1-kinase (2.7.1.134); IP5K, inositol pentakisphosphate 2-kinase (2.7.1.158; also known as IPK1); IP6K, inositol hexakisphosphate kinase (2.7.4.21).