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. Author manuscript; available in PMC: 2022 Aug 10.
Published in final edited form as: Adv Biol Regul. 2018 Oct 27;71:118–127. doi: 10.1016/j.jbior.2018.10.006

Fig. 6. Conserved aspects of nucleotide binding for PKA, PI3K and InsP kinases.

Fig. 6.

Shown is a graphical representation of highly conserved elements of protein kinases, PI3Ks and PDKG-InsPKs. Broken lines depict charged and polar contacts. For an explanation of catalytic triad, see Fig. 4 D,E,F and the text. ‘Catalytic K/H’ refers to the transition state stabilizing residue in the DxK/H motif (Table 1). See text and Table 1 for other details.