Table 3.

Antibiotics

Sr. no.	Antibiotic (pregnancy cat.)	Safety profile	Risk	Special points	References
1.	Penicillin (B)	Safe	–	–	[1,13,75]
2.	Cephalosporin (B)	Safe	–	–	[1,13,75]
3.	Azithromycin (B)	Safe	–	Used when penicillin allergy suspected	[1,13,75]
4.	Erythromycin base (B)	Safe	Estolate form asso. with risk of cholestatic jaundice in mother	Used when penicillin allergy suspected	[1,13,75]
5.	Metronidazole (B)	Safe	–	–	[13]
5.	Cotrimoxazole (D)	Unsafe	Fetal hyperbilirubinemia	Esp in second trimester	[1,76]
6.	Doxycycline (D)	Unsafe	Brown discoloration of teeth	–	[1]
7.	Tetracycline (D)	Unsafe	Brown discoloration of teeth, Enamel toxicity, decreased bone development in infant	–	[1,8,13]
8.	Fluoroquinolones (C)	Unsafe	Cartilage defects	–	[1,8]
9.	Clindamycin (B)	Avoided	Abnormal LFT, pseudomembranous colitis in mother	–	[8]
10.	Sulphonamides (C)	Unsafe	Fetal hyperbilirubinemia with kernicterus	–	[8]
11.	Aminoglycosides (D)	Unsafe	Fetal ototoxicity	–	[8,13]
12.	Chloramphenicol (C)	Unsafe	Grey baby syndrome, fetal death, maternal blood dyscrasias	–	[8]