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. 2022 Aug 9;17:43. doi: 10.1186/s13722-022-00321-6

Table 4.

Differences in nurse practitioner and physician assistant perceived efficacy of buprenorphine, methadone, and naltrexone

Perceived efficacy Formulation df Friedman test statistic Q Pa
Buprenorphine
n (%)
Methadone
n (%)
Naltrexone
n (%)
Decreases risk of death from an opioid overdose
 Agree 157 (86) 119 (58) 117 (71) 2 39.58  < 0.001
 Neither 19 (10) 44 (22) 42 (25)
 Disagree 7 (4) 41 (20) 6 (4)
Decreases cravings for opioids
 Agree 164 (90) 149 (73) 112 (67) 2 36.03  < 0.001
 Neither 14 (8) 32 (16) 40 (24)
 Disagree 4 (2) 23 (11) 15 (9)
Decreases rates of relapse
 Agree 146 (82) 118 (58) 111 (67) 2 25.04  < 0.001
 Neither 26 (15) 54 (27) 49 (29)
 Disagree 6 (3) 31 (15) 6 (4)
Works well in clients with co-occurring mental health disorders
 Agree 143 (79) 103 (52) 99 (60) 2 32.29  < 0.001
 Neither 32 (18) 71 (36) 64 (38)
 Disagree 5 (3) 25 (12) 3 (2)
Should be supplemented by mental health counseling
 Agree 155 (90) 172 (84) 129 (77) 2 7.79 0.020
 Neither 13 (7) 26 (13) 39 (23)
 Disagree 5 (3) 6 (3) 0
Should be supplemented by participation in peer support groups
 Agree 156 (87) 166 (81) 125 (74) 2 7.80 0.020
 Neither 18 (10) 33 (16) 42 (25)
 Disagree 5 (3) 5 (3) 2 (1)
Efficacy is improved by adding mental health counseling
 Agree 166 (91) 175 (88) 132 (79) 2 14.90 0.001
 Neither 14 (8) 24 (12) 34 (20)
 Disagree 2 (1) 1 (0) 1 (1)
Appropriate for unstable patients
 Agree 68 (39) 50 (25) 67 (41) 2 19.37 0.001
 Neither 58 (34) 67 (34) 68 (41)
 Disagree 46 (27) 82 (41) 30 (18)
Often diverted or misused
 Agree 67 (35) 94 (47) 12 (7) 2 91.95  < 0.001
 Neither 68 (35) 71 (36) 45 (28)
 Disagree 59 (30) 33 (17) 106 (65)

aP-Values for differences are from Friedman tests

Bold values indicate significance at 0.05