Table 2.
The association between overall prediabetes, IFG, IGT and elevated HbA1c and increased baPWV in middle-aged and old adults
| Age < 60 years | Age ≥ 60 years | P for interaction | Young:Old ROR | |||
|---|---|---|---|---|---|---|
| OR (95% CI) in Model 1 | OR (95% CI) in Model 2 | OR (95% CI) in Model 1 | OR (95% CI) in Model 2 | |||
| NGR | 1.00 | 1.00 | 1.00 | 1.00 | – | – |
| Prediabetes | 1.44 (1.07–1.94) | 1.36 (1.00-1.86) | 0.82 (0.63–1.08) | 0.89 (0.67–1.18) | 0.003 | 1.87 (1.25–2.81) |
| IFG | 1.64 (1.16–2.31) | 1.71 (1.20–2.44) | 0.95 (0.68–1.33) | 0.98 (0.70–1.39) | 0.006 | 1.99 (1.22–3.23) |
| IGT | 1.30 (0.94–1.81) | 1.31 (0.92–1.86) | 0.59 (0.44–0.80) | 0.61 (0.44–0.83) | < 0.001 | 2.67 (1.70–4.20) |
| Elevated HbA1c | 1.46 (1.09–1.95) | 1.38 (1.02–1.87) | 1.04 (0.80–1.36) | 1.13 (0.86–1.48) | 0.067 | 1.45 (0.98–2.16) |
The ORs of prediabetes were calculated compared to normal glucose regulation. The ORs of IFG were calculated compared to normal FPG, and those of IGT were estimated compared to normal 2 h-PPG, and those of elevated HbA1c were calculated compared to normal HbA1c. Model 1: adjust for age and sex; Model 2: adjust for age, sex, SBP, DBP, BMI, TG, LDL-C, HDL-C, uric acid, eGFR, smoking, drinking and anti-hypertensive drug
OR, odds ratio; CI, confidence interval; ROR, ratio of odds ratio; baPWV, branchial-ankle pulse wave velocity; NGR, normal glucose regulation; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; HbA1c, glycated hemoglobin; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate